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At a recent networking event for Massachusetts eHealth Institute (MeHI) startup and sandbox partners, Tatiana Urman, MSN, participated in a panel discussion and spoke about the Center for Clinical and Translational Research (CCTR).

One of the notable success stories to emerge from a CCTR collaboration, REEV, has recently closed a $9.2 million funding round. The company is developing DREEVEN, an AI-powered robotic knee brace designed to reduce muscle fatigue and restore mobility for individuals with multiple sclerosis or those recovering from a stroke or spinal cord injury. REEV's collaboration with the CCTR was supported in part by a Sandbox Rolling Grant from MeHI, which enabled the company to address critical research questions.

Tal Research Group, responsible for the Maestro study being run with the help of the CCTR, recently posted a preprint related to information discovered in another study currently headed by the lab. In a mouse model, the researchers observed persistent infection of the female reproductive tract up to 15 months post-inoculation, leading to uterine glandular cysts, endometrial hyperplasia, and vaginal epithelial changes. Additionally, analysis of electronic health records indicated that Lyme disease is associated with higher risks of menorrhagia, miscarriage, uterine fibroids, and endometriosis.